School of Medicine / Graduate School of Medicine / Graduate  School of Biomedical Science and Engineering / Faculty of  Medicine, Hokkaido University

Doctoral Dissertations 2014

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※ Students enrolled in April, 2007 or later

Degree conferred on December 25, 2014

Phthalates in house dust and their association with building characteristics and allergic symptoms
Studies on correction for variations of standardized uptake values on 18F-fluorodeoxyglucose positron-emission tomography in patients with lung cancer
Elucidating the role of microRNA-101 as a new therapeutic target for aggressive endometrial cancer
Hydrogen Sulfide Ameliorates Hepatic Warm Ischemia and Reperfusion Injury via Augmentation of Survival Signals and Nuclear Translocation of Nrf2
The pathogenesis and treatment of respiratory tract infections in children : Human bocavirus and influenza virus infections.
The clinicopathological study of Epithelial-Mesenchymal Transition (EMT) in Extrahepatic Bile Duct Carcinoma
Predicting lymph node involvement in patients with primary non-small cell lung cancer

Degree conferred on September 25, 2014

Integrated Morphological and Functional Evaluation of the Heart using MDCT and PET
Studies on hepatitis C virus infection in human B cells
Studies on STAT1 gain-of-function mutation responsible for chronic mucocutaneous candidiasis:two novel mutations, cytokine production profiles, and anti-IL-17F autoantibodies

Degree conferred on June 30, 2014

The role of Syndecan-4 in the development of autoimmune arthritis
The treatment, prognosis and its predictive factors of interstitial lung diseases associated with autoimmune diseases.
The synovial proliferative effect of Ras guanine nucleotide-releasing protein 4 in fibroblast-like synoviocytes

Degree conferred on March 25, 2014

Analysis of mechanism of adaptor protein Crk-induced epithelial-mesenchymal transition (EMT) and its implication to human cancer metastasis
The diagnostic system for hereditary interstitial lung disease in Japan
Impact of Proteasomal Dysfunction in Sensory Retina
The analysis of the association of the radiosensitivity and HIF-1 and Notch pathway
The effect and mechanism of pirfenidone in keloid-derived fibroblasts
Compound mutations cause increased cardiac events in children with Long QT syndrome
The effect of dexmedetomidine on the rat hippocampal synaptic plasticity
Analysis of the role for Notch1 in head and neck squamous cell carcinoma
Lack of Molecular-Anatomical Evidence for GABAergic Influence on Axon Initial Segment of Cerebellar Purkinje Cells by the Pinceau Formation
Functional analysis of FIP1L1-RARA and FIP1L1-PDGFRA; the leukemogenic fusion genes associated with FIP1L1.
Neonatal isoflurane exposure disturbs granule cell migration in the rat dentate gyrus
Effects of prenatal exposure to perfluoroalkyl acids on allergic diseases in early childhood
Cardiac magnetic resonance has better performance for the detection of functionally significant coronary artery stenosis compared to single-photon emission computed tomography and dobutamine stress echocardiography
Expression and proliferative activity of neuromedin B in pituitary adrenocorticotropin-producing cells
The mechanisms of morphological and functional changes in the bladder with partial bladder outlet obstruction
Is milnacipran a promising agent to suppress impulsive behavior?
High and low negative pressure suction techniques in endoscopic ultrasound-guided fine needle tissue acquisition using 25-gauge needles: A multicenter prospective randomized controlled trial
Adverse Effects of Maternal Passive Smoking during Pregnancy and Polycyclic Aromatic Hydrocarbon-metabolizing Genes on Birth Size
Randomized controlled trial on the skin toxicity of panitumumab in third line treatment of KRAS wild-type metastatic colorectal cancer.: HGCSG1001study [Japanese Skin Toxicity Evaluation Protocol with Panitumumab: J-STEPP]
Elucidating the Mechanisms of Chronic Inflammation Focusing on Natural Killer T Cells
Studies on mouse model generated by using PBMCs and the skin of Stevens-Johnson syndrome/ toxic epidermal necrolysis patients
Application of nuclear imaging in assessing therapeutic effects of bone marrow stromal cell transplantation for ischemic stroke in rats
Quantitative investigation of choroidal circulation for retinochoroidal diseases
Relationship between serum HER2 level and tissue HER2 status in patients with advanced/recurrent gastric cancer
Studies on Osteoarthritis with GM3 Synthase KO Mice
Validation of the Treatment Strategy for Spinal Dural Arteriovenous Fistulae Based on the Long-term Outcome
High-Expression of AMAP1 and EPB41L5 Proteins Correlates with Lymph Node Metastasis and Survival Rate after Surgical Therapy of HNSCC.
The sequential clinicopathological changes in pediatric patients with IgA nephropathy treated with corticosteroids: An analysis using the Oxford classification
Post-ischemic intra-arterial infusion of liposome-encapsulated hemoglobin can reduce ischemia reperfusion injury
Endoscopic diagnosis of early squamous neoplasia of the esophagus with narrow band imaging: Correlations among background coloration, pink-color sign on iodine staining and clinicopathological findings
The association between mechanical ventilation, flue use in heaters and asthma symptoms
Novel Molecular Targets for Treatment of Ocular Neovascular Diseases
Functional Analysis of Epileptic Spikes at Focal Cortical Dysplasia with Spatial Filtering Analysis
Studies on pathogenicity of obligate anaerobes in lower respiratory tract
Studies on image guided radiotherapy for bladder cancer
Function of small Maf transcriptional factors on pancreatic beta-cells and incretin effects
In Vivo Effects of Intra-articular Administration of Hyaluronic Acid on Hyaline Cartilage Regeneration Induced by Implantation of PAMPS-PDMAAm Double-network Hydrolgel
Novel Pharmacological Approach to Treatment of Ocular Neovascular Diseases
Studies on protein S-glutathionylation and glutaredoxin 1 in allergic airway inflammation
Studies on the Effect of Dipeptidyl Peptidase-4 Inhibitor on Exercise Capacity and Energy Metabolism in the Skeletal Muscle from the Experimental Heart Failure after Myocardial Infarction in Mice
Studies on induction of effective anti-tumor immunity and regulatory mechanisms by novel long peptide vaccination
The study of factors about post-procedural bleeding in endoscopic interventions
Molecular pathological analyses of CRK-DOCK related signaling molecules
Safe and efficient expansion of human bone marrow stromal cells in platelet lysate and granulocyte-colony stimulating factor (G-CSF) for cell therapy
Caspase 3 Silencing Inhibits Biomechanical Overload-induced Intervertebral Disc Degeneration
Biological roles of SOX2 and mechanisms of regulation of its expression in human breast cancer cells