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Professors and Research Fields

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As of November 16, 2017

  • Specially Appointed Professor
  • Visiting Professor
  • concurrent
  • Collaborative Laboratory Established by Collaboration among Universities
  • Research Archives Research Archives

Division of Medicine

Physiological Science

Biochemistry

Molecular Biology

Hisataka Sabe

  1. Cell integrity based on cellular metabolisms and nuclear geometry
  2. Nano structures controlling organelle dynamics
  3. Molecular bases of cancer therapeutic resistance

Medical Chemistry

Shigetsugu Hatakeyama Research Archives

  1. Ubiquitin system in protein degradation
  2. Intracellular signal in cancer and immune system
  3. Ubiqutination in regulation of gene expression

Anatomy

Anatomy and Embryology

Masahiko Watanabe Research Archives

  1. Visualization of expression and localization of neural signaling molecules
  2. Glial roles in neural development and function
  3. Molecular mechanisms for synaptic circuit development

Histology and Cytology

Toshihiko Iwanaga

  1. Functional morphology of gastrointestinal and genital tracts
  2. Histochemistry of transporters for nutrients
  3. Regulatory mechanism of cell growth, adhesion, and signaling by lectins
  4. Sensing mechanism in the mechanical and chemical sensory apparatuses

Physiology

Cel Physiology

Yusuke Ohba Research Archives

  1. Visualization of cell functions using fluorescence bioimaging
  2. Spatiotemporal regulation of intra-and intercellular signal transduction
  3. Regulation of membrane dynamics
  4. Development and application of fluorescent biosensors

Systems Neuroscience

Masaki Tanaka Research Archives

  1. Neural control of voluntary movements
  2. Functional analysis of the frontal cortex
  3. Functional analysis of the cortico-basal ganglia loop
  4. Functional analysis of the cerebro-cerebellar interaction

Pharmacology

Neuropharmacology

Mitsuhiro Yoshioka Research Archives

  1. Neuropharmacological studies of the serotonergic system development and its dysfunction
  2. Neuropharmacological studies of the relationship between stress and emotional system
  3. Neuropharmacological studies of impulsivity
  4. Functions and molecular basic of local neuronal circuits for fear and anxiety

Cellular and Molecular Pharmacology

Mitsuhiro Yoshioka

  1. Regulation of intracellular trafficking of G-protein coupled receptors
  2. Regulation of Ca2+ entry by G-protein coupled receptors
  3. Aberrant endothelin receptor signaling and onset/progression of pulmonary hypertension, diabetes mellitus and arteriosclerosis
  4. Identification of cytotoxic factors in cigarette smoke and molecular mechanisms for onset/progression of smoking-related diseases

Pathological Science

Pathology

Pathology

Masanori Kasahara

  1. Major histocompatibility complex and natural killer receptors
  2. Role of proteasomes in health and disease
  3. Pathogenesis of autoimmune diseases
  4. Tumor immunology
  5. Cancer stem cells
  6. Human pathology and surgical pathology

Cancer Pathology

Shinya Tanaka Research Archives

  1. Research for diagnostic and surgical pathology
  2. Analysis of brain tumor, soft tissue tumor, and respiratory disease
  3. Cancer stem cell research and drug development
  4. Signal transduction for various diseases including cancer
  5. Development of new bioimaging techniques for clinical application
  6. Translational pathology: Profiling analysis for decision of therapeutic agents
  7. Individual research based on student's interests

Diagnostic Pathology

Yoshihiro Matsuno

  1. Diagnostic surgical pathology (including cytopathology)
  2. Application of molecular studies in diagnostic pathology
  3. Quality control and standardization in pathology laboratories
  4. Clinicopathologic analysis of human malignancy

Microbiology and Immunology

Microbiology and Immunologyy

Koichi Kobayashi

  1. Host protection mediated by TLR and NLR family proteins
  2. Nod2-dependent intestinal mucosal homeostasis and pathogenesis of Crohn's disease
  3. CITA/NLRC5: a key regulator of MHC class I genes
  4. Mechanisms of immune evasion by cancers

Microbiology and Infectious Diseases

Jiro Arikawa

  1. Studies on the mechanism of pathogenicity of virus infection through molecular biological analysis and animal experimentation
  2. Studies on the diagnosis of infectious diseases
  3. Epidemiological study of zoonosis

Social Medicine

Social Medicine

Hygiene

Hiroshi Nishiura

  1. Epidemiological studies of infectious diseases
  2. Theoretical epidemiology and bioinformatics using mathematical and statistical models
  3. Global health studies with particular focus on infectious diseases
  4. Application of mathematical models including risk analysis, demography and population dynamics
  5. Hygiene and environmental health studies (consultation in advance is required)

Public Health

Akiko Tamakoshi Research Archives

  1. Field study on diet and health
  2. Studies on unhealthy status and its related factors of the elderly
  3. Longitudinal study of age-related neuropsychiatric function among a community-based elderly
  4. Studies on lifestyle factors and health in adults
  5. Research on ELSI (Ethical, Legal and Social Issues) of epidemiological studies

Forensic Medicine

Mitsuhiro Yoshioka

  1. Studies on medico-legal diagnosis of cause of death, post-mortem interval, wounds, asphyxia and identification
  2. Studies on the mechanisms of generation concerning exogeneous unusual findings

Health Care Policy

Akiko Tamakoshi

  1. Study on measures of healthcare and welfare for community-dwelling people in low fertility and ageing society
  2. Epidemiological study on HIV/AIDS/STIs and other includes Zoonosis and Life-Related diseases
  3. Study on risk perception/management/communication for infectious diseases
  4. Development of indicators to measure/raise community awareness against diseases

Biostatistics

Mitsuhiro Yoshioka

  1. Studies on the methodology of clinical trials
  2. Studies on the methodology of drug safety data analysis
  3. Studies on the multivariate data analysis

Medical Education and General Medicine

Junji Otaki

  1. Development of innovative teaching methods and materials
  2. Development of innovative evaluation methods
  3. Studies on factors that affect learning behavior
  4. Studies on training of general practitioners and their role in communities

Regulatory Science

Teruyo Arato

  1. Studies on non-clinical data necessary for the development of advanced biological medicines
  2. Studies on clinical data-packages for orphan drugs
  3. Studies on criteria for approval of biosimilar products
  4. Studies on post marketing surveillance of pharmaceuticals and medical devices

Translational Research Management

Norihiro Sato

  1. Methodology of clinical research
  2. Data management of clinical trial
  3. Management of cell processing for cell therapy and regenerative medicine
  4. Methodology of translational research support

Patient Safety

Yasuyuki Nasuhara

  1. Development of appropriate indices of assessment for preventing falls
  2. Development of effective alert system against clinicians in electrical medical charts
  3. Development of standardized methods in investigation of medical accidents

Pharmaceuticals and Medical Devices Regulatory Science

Internal Medicine

Internal Medicine

Respiratory Medicine

Masaharu Nishimura, Ichizo Tsujino

  1. Prospective cohort studies of asthma and/or COPD
  2. Research on molecular mechanisms, diagnosis, and treatment of thoracic malignancies
  3. Research on molecular mecahnisms of chronic airway disease and/or diffuse lung disease
  4. Basic/clinical research on pulmonary hypertension and cardiac sarcoidosis
  5. Basic/clinical research on respiratory infectious diseases
  6. Basic/clinical research on obesity and dysregulated glucose/lipid/protein metabolism

Rheumatology, Endocrinology and Nephrology

Tatsuya Atsumi Research Archives

  1. Basic and clinical research on autoimmune disorders
  2. Research on the pathophysiology, diagnosis and therapy of diabetes, obesity and dyslipidemia
  3. Research on the pathophysiology and therapy of endocrine diseases
  4. Basic and clinical research on renal diseases

Gastroenterology and Hepatology

Naoya Sakamoto

  1. Research for pathophysiology, diagnosis and treatment of liver diseases
  2. Research for pathophysiology, diagnosis and treatment of pancreatobiliary diseases
  3. Research for pathophysiology, diagnosis and treatment of malignant tumor of digestive system
  4. Research for pathophysiology and treatment of inflammatory bowel diseases
  5. Research for pathophysiology, diagnosis and treatment of digestive diseases

Cardiovascular Medicine

Toshihisa Anzai

  1. Research on pathophysiology, diagnosis, and treatment for ischemic heart disease
  2. Molecular biological and clinical research on pathophysiology and treatment for heart failure
  3. Research on etiology, diagnosis, and treatment for idiopathic cardiomyopathy
  4. Research on molecular and genetic basis, diagnosis, and treatment for hypertension
  5. Research on etiology, diagnosis, and treatment for arrhythmia
  6. Development of non-invasive technique for diagnosis of heart disease

Medical Oncology

Hirotoshi Akita Research Archives

  1. Research on diagnosis and treatment of malignant tumors
  2. Research on molecular pathophysiology, diagnosis and treatment of lung cancers and mediastinal tumors
  3. Research on molecular pathophysiology, diagnosis and treatment of tumors of the digestive organs
  4. Research on cancer drug therapy
  5. Research on molecular targeting therapy of cancer
  6. Research on genome analysis, companion diagnostics and precision medicine of cancer

Hematology

Takanori Teshima Research Archives

  1. Research on molecular pathogenesis, diagnosis, treatment of hematological malignancies
  2. Basic and clinical researches to improve outcome of hematopoietic stem cell transplantation
  3. Basic research to understand cellular & molecular biology of hematopoiesis
  4. Basic and clinical researches on cell therapies against viral infections and malignant diseases
  5. Pathogenesis, diagnosis, and treatment of immunodeficiencies, including AIDS
  6. Blood transfusion medicine

Health Care Medicine

Satoshi Hashino

  1. Research for impaired health caused by stresses
  2. Research for evidence based medicine in health examination
  3. Research for hematopoietic diseases induced by hazardous materials
  4. Research for immune thrombocytopenia
  5. Research for complications and adverse events of treatment in HIV infection

Radiology

Radiation Medicine

Mitsuhiro Yoshioka

  1. Radiation Usage in Medical Research
  2. Diagnostic radiology using CT, MRI, and ultrasound
  3. Interventional radiology and vascular diagnostic imaging
  4. Neuroradiology
  5. Cardiac radiology
  6. Advanced X-ray Therapy
  7. Medical physics
  8. Radiobiology for Radiotherapy
  9. Particle Therapy, Proton Therapy

Nuclear Medicine

Mitsuhiro Yoshioka

  1. Nuclear medicine diagnosis
  2. Tracer kinetics of nuclear medicine
  3. PET study
  4. Synthesis of radiopharmaceuticals
  5. Instrumentation of nuclear medicine
  6. Radioisotope treatment
  7. Molecular imaging

Comprehensive Radiological Science

Tadashi Kamada , Keiichiro Yoshinaga , Tatsuya Azuma

  1. Comprehensive research of diagnostic radiology, nuclear medicine, and radiation oncology
  2. Basic translational research from oncological diagnosis to treatment
  3. Clinical translational research from oncological diagnosis to treatment
  4. Comprehensive research of radiological science based on combination of biomedical science and engineering

Surgery

Surgery

Gastroenterological Surgery I

Akinobu Taketomi

  1. Pathophysiology of alimentary tract diseases and their surgical managements
  2. Hepato-biliary-pancreatic malignancy and their surgical treatments
  3. Liver transplantation and artificial hepatic support
  4. Perioperative management, non-parenteral nutrition and multi-system organ failure
  5. Surgical oncology
  6. Echinococcosis
  7. Basic research and treatment on pediatric surgical oncology and pediatric hepatobiliary diseases
  8. Basic and clinical research on the function of pediatric digestive system

Gastroenterological Surgery II

Satoshi Hirano Research Archives

  1. Clarification of pathogenesis and development of surgical treatments of the malignancy of the digestive system
  2. Development of endoscopic surgery and its devices
  3. Clinical research for perioperative management of highly invasive digestive surgeries
  4. Study for multidisciplinary treatment of pancreato-biliary cancer
  5. Molecular research on biomarkers associated with oncological malignancy
  6. Exploring translational research on immunotherapy
  7. Analysis of immune responses in the tumor microenvironment
  8. Study of gene therapy for intractable cancers

Renal and Genitourinary Surgery

Nobuo Shinohara

  1. The mechanism of development of detrusor overactivity associated with lower urinary tract obstruction
  2. Neural transmitted pathway at the bladder stimulation
  3. The development of chronic rejection in transplanted kidney
  4. The analysis of immunology in renal transplantation and development of the treatment of immunological regulation
  5. The mechanism of carcinogenesis and progression in kidney cancer
  6. The mechanism of metastasis and progression of urothelial cancer
  7. QOL study on the treatment of prostate cancer
  8. The development of minimal invasive surgery

Cardiovascular and Thoracic Surgery

Yoshiro Matsui

  1. Innovation of surgical intervention on severe congestive heart failure
  2. Research on extracorporeal circuit
  3. Autophagy in left ventriculoplasty
  4. Insulin resistance in postoperative atrial fibrillation
  5. Basic research on aortic valve plasty
  6. Endovascular stent graft therapy for aortic disease
  7. Development of minimally invasive thoracic surgery
  8. Surgery for lung cancer after chemoradiotherapy
  9. Lung transplantation
  10. Tumor angiogenesis of thoracic malignant tumors

Breast Surgery

Hiroko Yamashita

  1. Research on biological characteristics in breast cancer
  2. Research on endocrine therapy in breast cancer
  3. Research on mechanisms of breast cancer development and prevention

Anesthesiology and Critical Care Medicine

Anesthesia and Perioperative Medicine

Yuji Morimoto

  1. Cerebral protection and resuscitation
  2. Circulatory, respiratory and neuronal responses to the perioperative stress (surgical, etc)
  3. Neurotoxicity by anesthetics
  4. Mechanism of general anesthesia
  5. Mechanism and treatment of pain
  6. Mechanism of respiratory cycle and effect of drugs
  7. Hyperbaric oxygen therapy
  8. Patient management system in the operating room and the medical economics

Acute and Critical Care Medicine

Satoshi Gando

  1. Body responses to various insults - pathophysiology and their control -
  2. Multiple organ dysfunction syndrome - pathophysiology and treatment -
  3. Critical care medicine
  4. Cardiopulmonary cerebral resuscitation
  5. Toxicology
  6. Traumatology
  7. Disaster medicine
  8. Medical, transportation, and information system for acute medicine

Specialized Medicine

Reconstructive Surgery and Rehabilitation Medicine

Orthopedic Surgery

Norimasa Iwasaki Research Archives

  1. Tissue engineering for musculoskeletal tissue repair
  2. Etiology and pathogenesis of osteoarthritis
  3. Role of glycans and these regonizing molecules in bone and cartilage metabolism
  4. Pathophysiology of secondary osteoporosis
  5. Study of intervertebral disc apoptosis for prevention of the disc regeneration
  6. Basic research for elucidation of rheumatoid arthritis pathogenesis
  7. Regulation of arthritis and osteolysis by manipulation of inflammation
  8. Biomechanical evaluation of surgical efficacy for musculoskeletal disorders
  9. Regenerative medicine for spinal cord injury and peripheral nerve injury

Regenerative Medicine

Norimasa Iwasaki

  1. Research on molecular mechanisms of remodeling of the soft tissue graft materials in ligament reconstruction
  2. Development of tissue engineering scaffolds and artificial organs
  3. Development of in vivo spontaneous tissue regeneration strategies with clinical applicable biomaterials
  4. Development of minimally invasive surgery for the bone and the joint

Plastic and Reconstructive Surgery

Yuhei Yamamoto

  1. Translational research in wound healing
  2. Translational research in treatment of keloid
  3. Development of surgical technique in free tissue transfer
  4. Basic research in surgical oncology
  5. Translational research of angiogenesis of vascular and lymphatic vessel
  6. Regenerative medicine based on tissue engineering method
  7. Development of therapeutic technique in cranio-maxillo-facial surgery

Rehabilitation Medicine

Katsunori Ikoma

  1. Studies on functional recovery from the damage of the nervous system and plasticity
  2. Studies on higher brain function and its rehabilitation
  3. Studies on neurophysiological analyses
  4. Studies on pain control
  5. Molecular biological studies of muscle strengthening

Reproductive and Developmental Medicine

Pediatrics

Tadashi Ariga

  1. Molecular genetic research of primary immunodeficient diseases
  2. Molecular biological research for viral infectious disease in children
  3. Clinical and basic research for malignant diseases in children
  4. Clinical and basic research for endocrine diseases in children
  5. Clinical and basic research for neuro-muscular diseases in children
  6. Clinical and basic research of chromosomal abnormality and dysmorphology
  7. Immunopathological research for renal diseases in children
  8. Clinical and basic research for cardiovascular diseases in children
  9. Clinical and basic research in perinatal medicine
  10. Clinical and basic research of inheritant metabolic diseases
  11. Clinical and basic research of gene therapy

Obstetrics and Gynecology

Tadashi Ariga

  1. Studies on the cell biology involved in the cause of spontaneous abortion
  2. Basic studies on the physiology of fetus and amnion
  3. Clinical studies on the antenatal diagnosis and fetal therapy
  4. Studies on the development of new strategy for the management of complicated pregnancies
  5. Studies on the prophylaxis of preterm birth
  6. Studies on the prophylaxis of osteoporosis
  7. Studies on the regulation of osteoclasts
  8. Clinical studies on the treatment of infertility
  9. Intrafollicular physiology
  10. Regulatory mechanism of ovulation
  11. Molecular mechanism of genesis and metastasis of uterine cancer
  12. Novel treatment strategy for advanced cervical cancer
  13. Immunotherapy for ovarian cancer
  14. Chemoresistance of female reproductive cancer
  15. Molecular research of health maintenance in middle to elderly-aged women
  16. Molecular mechanism of placental growth and differentiation

Sensory Organ Medicine

Dermatology

Hiroshi Shimizu

  1. Molecular biological research of epidermis
  2. Research on pathophysiology, diagnosis and treatment of genetic skin disorders
  3. Research on pathophysiology, diagnosis and treatment of autoimmune skin diseases
  4. Research on pathophysiology, diagnosis and treatment of malignant skin tumors
  5. Research on pathophysiology, diagnosis and treatment of atopic dermatitis
  6. Research on tissue engineering and wound healing
  7. Research on hair regeneration, and treatment of alopecia
  8. Research on novel therapeutic modalities for genetic skin disorders

Otolaryngology-Head and Neck Surgery

Akihiro Honma

  1. Basic research and clinical analysis for pathogenesis of sensorineural hearing loss
  2. Basic research and clinical analysis of sensorineural hearing loss by viral infection
  3. Basic research and clinical analysis of nasal allergy
  4. Basic research and clinical analysis of IgG4 related disease
  5. Immunological approach for head and neck cancer
  6. Basic research and clinical analysis of chemotherapy for head and neck cancer
  7. Molecular biologic studies on head and neck cancer

Ophthalmology

Susumu Ishida Research Archives

  1. Retinal cell biology
  2. Pathophysiology and treatment of uveitis
  3. Molecular genetics of ocular diseases
  4. Pathophysiology and treatment of ocular surface disease
  5. Ocular circulation
  6. Neuroprotection for glaucoma

Neurological Disorder

Psychiatry

Ichiro Kusumi

  1. Psychopathology of psychiatric diseases
  2. Development of new psychotherapy techniques
  3. Development of new diagnostic techniques and new treatment of epilepsy
  4. Molecular genetic study of psychiatric diseases
  5. Development of animal models of psychiatric diseases and neuroscience
  6. Development of new psychotropic drugs and psychopharmacology
  7. Neuroimaging in psychiatric diseases
  8. Neurophysiological and neuropsychological study of psychiatric diseases

Neurosurgery

Kiyohiro Houkin

  1. Basic and clinical research on malignant glioma
  2. Basic and clinical research on cerebrovascular disorders
  3. Basic and clinical research on spinal cord disorders
  4. Translational research on CNS regeneration
  5. Surgical anatomy of skull base surgery
  6. Genomic research on cerebrovascular disorders
  7. Cerebral hemodynamics and metabolism
  8. Clinical research on pediatric neurosurgery

Neurology

Hidenao Sasaki

  1. Clinical neuroelectrophysiology
  2. Immunohistochemistry of muscles and peripheral nerves
  3. Molecular biology and genetics for neurological disorders
  4. Basic studies for the disease mechanism and therapeutic approach in neuroimmunological disorders
  5. Biomarkers in neurological disorders
  6. Cogitive brain function
  7. Neuroepidemiology

Interdisciplinary Medicine

Medical Biology

Neurobiology

Haruyuki Kamiya

  1. Neurobiology of axon
  2. Neurobiology of synapse

Human Evolution Studies

Mitsuhiro Yoshioka

  1. Evolution and functional adaptation of skeletal morphology
  2. Analysis of bone cross-sectional geometry using CT images
  3. Development of morphological analysis methods of human fossils
  4. Study on the pattern and mechanism of human evolution
  5. Human-environment relationships in Eurasian Paleolithic
  6. Archaeometry of obsidian
  7. Research on prehistoric cultures of Hokkaido

 

Immunology

Developmental Immunology

Masaaki Murakami

  1. To decipher molecular and cellular mechanism underlying generation of lymphoid tissues
  2. To decipher function of innate lymphoid cells in mouse and human
  3. Analysis of functionally important mesenchymal stromal cells in lymphoid tissues

Immunobiology

Kenichiro Seino

  1. Tumor Immmunology
  2. Transplant Immunology
  3. Development of a novel immune cell therapy using cell reprogramming technique

Functional Immunology

Masaaki Murakami

  1. Molecular and cellular mechanisms on the functional regulation of dendritic cells and its application to immune-related diseases
  2. Evaluation of IL-6 signaling-mediated immunosuppression
  3. Research on pathogenesis of severe asthma and chronic inflammation and development of the novel immunotherapy
  4. Identification of novel biomarkers for development of personalized medicine

Psychoimmunology

Masaaki Murakami

  1. Research for regulation of disease development by psychological states
  2. Research for interactions of organ functions by neural activation (the gateway reflexes)
  3. Research for molecular mechanisms underlying chronic inflammation in the CNS
  4. Research for novel tissue-specific mechanisms for enhancement of inflammation
  5. Development of novel drugs and biomarkers for diseases associated with chronic inflammation

Pathological Oncology

Cancer Biology

Masayuki Noguchi

  1. To study and characterize the intracellular signal transduction cascade that controls the balance between the cell death and survival

RNA Biofunction

Tetsurou Hirose

  1. Molecular mechanisms of noncoding RNA function
  2. Caracterization of RNA granules in cancer cells
  3. Noncoding RNA functions in neurodegenerative disease
  4. Primate-specific epigenetic regulation conducted by noncoding RNA
  5. Noncoding RNA evolution

Stem Cell Biology

Toru Kondo

  1. Molecular mechanism involved in the maintenance and differentiation of neural stem/precursor cells
  2. Molecular mechanism of neural stem/precursor aging
  3. Characterization of cancer stem cells and analysis of their therapeutic targets
  4. Relationship between neural stem cells and age-related disorders
  5. Studies on organ-preference of tumor metastases
  6. Analyses of expression-networks of metastasis-related genes
  7. Analyses of emergence and maintenance of diverse tumor cells

Division of Medical Science

Medical Science